Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GOT1 | P17174 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24783631 | 0.79 | NCF1 (0.55) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL1998971 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL5272072 | 0.76 | MAPT (0.50) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL12890445 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL1998972 | 0.75 | KDM4E (0.42) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL3071109 | 0.71 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL2014209 | 0.71 | KDM4E (0.50) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL5321887 | 0.71 | SLC2A1 (0.44) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL5483645 | 0.70 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL31115164 | 0.70 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073625-B | Reduced and oxidized polysaccharides and methods of use thereof | 哈佛学院院长等 | 2024-01-16 | — | — | CN | disclosed |
| CN-117337190-A | Folate receptor targeted conjugates, compositions and delivery to the central nervous system | 普渡研究基金会 | 2024-01-02 | — | — | CN | disclosed |
| CN-110585420-B | Medical application of CREG protein to protection of high-salt-induced kidney injury | 中国人民解放军北部战区总医院 | 2023-07-21 | — | — | CN | disclosed |