Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | VNN1 | O95497 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30661275 | 1.00 | CCNE2 (0.55) | CCNE2CCNE1CDK2VNN1HTT | |
| SCHEMBL19407673 | 0.86 | VNN1 (0.56) | CCNE2CCNE1CDK2VNN1CDK1 | |
| SCHEMBL29019899 | 0.86 | CCNE2 (0.57) | CCNE2CCNE1CDK2VNN1HTT | |
| SCHEMBL30395245 | 0.86 | CCNE2 (0.57) | CCNE2CCNE1CDK2VNN1HTT | |
| SCHEMBL29976549 | 0.85 | CCNE2 (0.56) | CCNE2CCNE1CDK2VNN1HTT | |
| SCHEMBL25976265 | 0.84 | CCNE2 (0.40) | CCNE2CCNE1CDK2LMNA | |
| SCHEMBL23642689 | 0.82 | CCNE2 (0.53) | CCNE2CCNE1CDK2VNN1HTT | |
| SCHEMBL18168568 | 0.82 | CCNE2 (0.53) | CCNE2CCNE1CDK2VNN1HTT | |
| SCHEMBL15584951 | 0.81 | APP (0.55) | VNN1CDK1MAPTEGFRNR2F2 | |
| SCHEMBL18757880 | 0.81 | NPC1 (0.62) | CCNE2CCNE1CDK2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043163-A | Pyrrolopyrimidine or pyrrolopyridine derivative and medical application thereof | 希格生科（深圳）有限公司 | 2023-11-10 | — | — | CN | disclosed |