Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134343 | 1.00 | THRB (0.42) | THRBATML3MBTL1CCR2EPHX1 | |
| SCHEMBL671290 | 0.92 | THRB (0.51) | THRBATML3MBTL1EPHX1EPHX2 | |
| SCHEMBL4122335 | 0.92 | THRB (0.47) | THRBATML3MBTL1EPHX1EPHX2 | |
| SCHEMBL4112587 | 0.92 | THRB (0.51) | THRBATML3MBTL1EPHX1EPHX2 | |
| SCHEMBL5202228 | 0.90 | THRB (0.54) | THRBATML3MBTL1EPHX1EPHX2 | |
| SCHEMBL4114698 | 0.90 | THRB (0.54) | THRBATML3MBTL1EPHX1EPHX2 | |
| SCHEMBL1308573 | 0.89 | THRB (0.46) | THRBATML3MBTL1EPHX1EPHX2 | |
| SCHEMBL3487568 | 0.88 | CA1 (0.41) | THRBATML3MBTL1EPHX2ALDH1A1 | |
| SCHEMBL27003453 | 0.88 | CA1 (0.41) | THRBATML3MBTL1EPHX2ALDH1A1 | |
| SCHEMBL28513626 | 0.88 | CA1 (0.41) | THRBATML3MBTL1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916238-A | Compositions and methods for inhibiting RAS | 瑟拉斯有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116997548-A | HTT modulators for the treatment of huntington's disease | CHDI基金会股份有限公司 | 2023-11-03 | — | — | CN | disclosed |