Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.68 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134827 | 0.88 | AR (0.53) | ARMAOBMAOAKDM4EUSP2 | |
| SCHEMBL29134917 | 0.83 | MAOB (0.56) | ARMAOBMAOAALDH1A1TUBB4A | |
| SCHEMBL29134515 | 0.82 | AR (0.64) | ARMAOBMAOAIMPDH2PGR | |
| SCHEMBL286644 | 0.80 | AR (0.53) | ARKDM4EUSP2ALDH1A1IDH1 | |
| SCHEMBL29964800 | 0.77 | ALDH1A1 (0.61) | ARMAOBMAOAKDM4EUSP2 | |
| SCHEMBL393816 | 0.77 | ALDH1A1 (0.61) | ARMAOBMAOAKDM4EUSP2 | |
| SCHEMBL31345528 | 0.76 | ALDH1A1 (0.56) | ARKDM4EALDH1A1TUBB4ATUBB | |
| SCHEMBL5094814 | 0.76 | AR (0.62) | ARMAOBMAOAKDM4EUSP2 | |
| SCHEMBL20389510 | 0.74 | MAOB (0.66) | ARMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL31061245 | 0.71 | AR (1.00) | ARMAOBMAOAIMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |