Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.56 |
| ▸ | MAOA | P21397 | 5/20 | 0.56 |
| ▸ | AR | P10275 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 2/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134531 | 0.83 | AR (0.68) | MAOBMAOAARALDH1A1TUBB4A | |
| SCHEMBL30909385 | 0.82 | MAOB (0.56) | MAOBMAOAARALDH1A1GAA | |
| SCHEMBL29134924 | 0.82 | AR (0.44) | MAOBMAOAARSTK10SLK | |
| SCHEMBL31345528 | 0.81 | ALDH1A1 (0.56) | ARALDH1A1GAAMAPTHPGD | |
| SCHEMBL29134408 | 0.81 | AR (0.52) | MAOBMAOAARALDH1A1GAA | |
| SCHEMBL29134827 | 0.80 | AR (0.53) | MAOBMAOAARALDH1A1 | |
| SCHEMBL2731932 | 0.78 | AR (0.66) | MAOBMAOAARL3MBTL1PTGIR | |
| SCHEMBL20132302 | 0.73 | MAOB (1.00) | MAOBMAOAALDH1A1IDO1 | |
| SCHEMBL27440272 | 0.71 | CYP1A1 (0.47) | MAOBMAOASTK10SLK | |
| SCHEMBL4347570 | 0.71 | PTGS1 (0.40) | ARMAPTTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |