SCHEMBL29134583

SCHEMBL29134583

Fc1ccc(-n2c3ccccc3c3ccccc32)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 2/20 0.43
GPR3 P46089 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.34
CNR1 P21554 3/20 0.34
CNR2 P34972 3/20 0.34
DUSP3 P51452 1/20 0.33
PDE7A Q13946 1/20 0.33
MPI P34949 1/20 0.32
CYP19A1 P11511 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
BACE1 P56817 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12414493 0.80 KDM4E (0.50) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL12019940 0.80 KDM4E (0.50) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL12019900 0.80 KDM4E (0.50) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL30634063 0.80 ALDH1A1 (0.52) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL24495915 0.80 ALDH1A1 (0.52) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL14557135 0.80 ALDH1A1 (0.55) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL23510074 0.77 SLC22A12 (0.45) KDM4EL3MBTL1ATMALDH1A1TSHR
SCHEMBL12019901 0.77 KDM4E (0.46) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL17950298 0.76 GLA (0.50) KDM4EL3MBTL1ATMALDH1A1TSHR
SCHEMBL13866720 0.76 L3MBTL1 (0.42) KDM4EL3MBTL1ATMALDH1A1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343059-B Naphthoimidazocarbazole compound and application thereof 烟台九目化学股份有限公司 2024-02-06 CN disclosed
CN-117343059-A Naphthoimidazocarbazole compound and application thereof 烟台九目化学股份有限公司 2024-01-05 CN disclosed