Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3874361 | 0.98 | CCR5 (0.43) | CCR5CA2CAMK2AAPOBEC3AAPOBEC3G | |
| SCHEMBL13714653 | 0.81 | POLB (0.43) | CCR5APOBEC3AAPOBEC3GHPGDUSP2 | |
| SCHEMBL2911826 | 0.79 | MAPT (0.42) | CA2CAMK2ACTDSP1AKR1B1ALDH1A1 | |
| SCHEMBL1961848 | 0.79 | APOBEC3A (0.48) | CCR5APOBEC3AAPOBEC3GCYP2D6CTDSP1 | |
| Bromide SCHEMBL3874702 | 0.78 | MAPT (0.41) | CA2CAMK2ACTDSP1AKR1B1ALDH1A1 | |
| SCHEMBL12682901 | 0.78 | CHRNA7 (0.44) | CCR5APOBEC3AAPOBEC3GCYP2D6CTDSP1 | |
| Hydrochloric Acid SCHEMBL10751415 | 0.78 | APOBEC3A (0.47) | CCR5APOBEC3AAPOBEC3GCYP2D6CTDSP1 | |
| SCHEMBL10257015 | 0.78 | APOBEC3A (0.47) | CCR5APOBEC3AAPOBEC3GCYP2D6CTDSP1 | |
| Water SCHEMBL4082000 | 0.78 | APOBEC3A (0.47) | CCR5APOBEC3AAPOBEC3GCYP2D6CTDSP1 | |
| Bromide SCHEMBL10751445 | 0.78 | APOBEC3A (0.47) | CCR5APOBEC3AAPOBEC3GCYP2D6CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517892-B1 | RING-SUBSTITUTED DIPHENYL AZETIDINONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND USE THEREOF | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-1517892-A1 | RING-SUBSTITUTED DIPHENYL AZETIDINONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND USE THEREOF | Aventis Pharma Deutschland GmbH (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000804-A1 | RING-SUBSTITUTED DIPHENYL AZETIDINONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND USE THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-31 | — | — | WO | disclosed |