Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 2/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1961848 | 0.98 | APOBEC3A (0.48) | APOBEC3AAPOBEC3GCYP2D6CTDSP1CHRNA7 | |
| Bromide SCHEMBL10751445 | 0.96 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GCYP2D6CTDSP1CHRNA7 | |
| SCHEMBL10257015 | 0.96 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GCYP2D6CTDSP1CHRNA7 | |
| Hydrochloric Acid SCHEMBL10751415 | 0.96 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GCYP2D6CTDSP1CHRNA7 | |
| Water SCHEMBL3683454 | 0.82 | CHRNA7 (0.58) | APOBEC3AAPOBEC3GCYP2D6CTDSP1CHRNA7 | |
| SCHEMBL12682901 | 0.81 | CHRNA7 (0.44) | APOBEC3AAPOBEC3GCYP2D6CTDSP1CHRNA7 | |
| Water SCHEMBL723735 | 0.80 | CHRNB2 (0.59) | APOBEC3AAPOBEC3GCYP2D6CTDSP1CHRNA7 | |
| Water SCHEMBL8939227 | 0.80 | CHRNB2 (0.59) | APOBEC3AAPOBEC3GCYP2D6CTDSP1CHRNA7 | |
| SCHEMBL3681307 | 0.79 | CHRNA7 (0.60) | APOBEC3AAPOBEC3GCYP2D6CTDSP1CHRNA7 | |
| SCHEMBL20017727 | 0.79 | CHRNA7 (0.43) | APOBEC3AAPOBEC3GCYP2D6CTDSP1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504527-B2 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING, LLC (US) | 2009-03-17 | — | — | US | disclosed |
| US-7491837-B2 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING LLC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-7145029-B2 | Low corrosive integrated process for preparing dialkyl carbonates | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-12-05 | — | — | US | disclosed |
| EP-1490323-A1 | A LOW CORROSIVE INTEGRATED PROCESS FOR PREPARING DIALKYL CARBONATES | ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20040236136-A1 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING, LLC | 2004-11-25 | — | — | US | disclosed |
| US-6774256-B2 | Low corrosive integrated process for preparing dialkyl carbonates | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-08-10 | — | — | US | disclosed |
| US-20040059083-A1 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING, LLC | 2004-03-25 | — | — | US | disclosed |
| US-20040054214-A1 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING, LLC | 2004-03-18 | — | — | US | disclosed |
| WO-2003082797-A1 | A LOW CORROSIVE INTEGRATED PROCESS FOR PREPARING DIALKYL CARBONATES | EXXONMOBIL CHEMICAL PATENTS INC. A CORPORATION OF THE STATE OF DELAWARE (US) | 2003-10-09 | — | — | WO | disclosed |
| US-20030023109-A1 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING, LLC | 2003-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236136-A1 | Low corrosive integrated process for preparing dialkyl carbonates | DCLK1, DGKI, GALK1 | APOBEC3A 409/4885APOBEC3G 493/4885CYP2D6 1273/4885 |
| US-20040054214-A1 | Low corrosive integrated process for preparing dialkyl carbonates | DCLK1, DGKI, GALK1 | APOBEC3A 409/4885APOBEC3G 493/4885CYP2D6 1273/4885 |
| US-20030023109-A1 | Low corrosive integrated process for preparing dialkyl carbonates | DCLK1, DGKI, GALK1 | APOBEC3A 409/4885APOBEC3G 493/4885CYP2D6 1273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.