Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24698078 | 0.89 | GBA1 (0.47) | GBA1L3MBTL1KDM4EALDH1A1PIK3CA | |
| SCHEMBL24698533 | 0.88 | GBA1 (0.46) | GBA1L3MBTL1KDM4EALDH1A1PIK3CA | |
| SCHEMBL24698426 | 0.86 | KARS1 (0.40) | GBA1KDM4EALDH1A1PIK3CAMTOR | |
| SCHEMBL24698066 | 0.86 | GBA1 (0.44) | GBA1L3MBTL1KDM4EALDH1A1PIK3CA | |
| SCHEMBL24698977 | 0.86 | GBA1 (0.41) | GBA1MAPTL3MBTL1KDM4EPIK3CA | |
| SCHEMBL24698990 | 0.83 | GBA1 (0.44) | GBA1KDM4EALDH1A1PIK3CAMTOR | |
| SCHEMBL24697795 | 0.81 | ALDH1A1 (0.40) | GBA1MAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL24698171 | 0.81 | ALDH1A1 (0.54) | GBA1MAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL24699076 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1PIK3CAMTORPIK3CG | |
| SCHEMBL24699410 | 0.80 | ALDH1A1 (0.38) | GBA1L3MBTL1KDM4EALDH1A1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |