Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 7/20 | 0.46 |
| ▸ | AURKA | O14965 | 5/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | CD38 | P28907 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28616596 | 0.74 | ADORA2A (0.49) | ADORA2AKMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL29049141 | 0.71 | ADORA2A (0.46) | ADORA2ANPC1RAB9AKMT2ALMNA | |
| SCHEMBL28617976 | 0.71 | ADORA2A (0.43) | ADORA2ARAB9AKMT2ASMN1; SMN2LMNA | |
| SCHEMBL19258239 | 0.71 | ADORA2A (0.56) | ADORA2ANPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL29158861 | 0.70 | NSD2 (0.43) | RPS6KB1AURKANPC1RAB9AKMT2A | |
| SCHEMBL27557206 | 0.69 | RXFP1 (0.45) | ADORA2ARAB9AKMT2ASMN1; SMN2LMNA | |
| SCHEMBL3075421 | 0.69 | ADORA2A (0.75) | ADORA2AAURKBNPC1RAB9AKMT2A | |
| SCHEMBL530286 | 0.69 | FABP4 (0.57) | KMT2ALMNAMAPTMYC | |
| SCHEMBL17099640 | 0.69 | PI4KA (0.52) | ADORA2AAURKBNPC1RAB9AKMT2A | |
| SCHEMBL31385237 | 0.69 | PI4KA (0.52) | ADORA2AAURKBNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |