Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 3/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ROS1 | P08922 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24699253 | 1.00 | PARP10 (0.40) | PARP10PARP11PARP1PNMTPBRM1 | |
| SCHEMBL30015440 | 1.00 | PARP10 (0.40) | PARP10PARP11PARP1PNMTPBRM1 | |
| SCHEMBL29134743 | 0.86 | PARP10 (0.40) | PARP10PARP11PARP1PNMTPBRM1 | |
| SCHEMBL30015575 | 0.86 | PARP10 (0.40) | PARP10PARP11PARP1PNMTPBRM1 | |
| SCHEMBL10197625 | 0.80 | PNMT (0.38) | PNMTCA2RXFP1 | |
| SCHEMBL24697374 | 0.78 | PBRM1 (0.50) | PARP10PARP11PARP1PBRM1CA2 | |
| SCHEMBL30016461 | 0.78 | PBRM1 (0.50) | PARP10PARP11PARP1PBRM1CA2 | |
| SCHEMBL23160392 | 0.78 | PBRM1 (0.50) | PARP10PARP11PARP1PBRM1CA2 | |
| SCHEMBL30017233 | 0.78 | PBRM1 (0.50) | PARP10PARP11PARP1PBRM1CA2 | |
| SCHEMBL29134751 | 0.78 | PBRM1 (0.50) | PARP10PARP11PARP1PBRM1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |