Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.77 |
| ▸ | MEN1 | O00255 | 7/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.77 |
| ▸ | THRA | P10827 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 5/20 | 0.77 |
| ▸ | PPARG | P37231 | 3/20 | 0.77 |
| ▸ | PCNA | P12004 | 2/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | GABRP | O00591 | 1/20 | 0.77 |
| ▸ | GABRD | O14764 | 1/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.77 |
| ▸ | F2 | P00734 | 1/20 | 0.77 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.77 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.77 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.77 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.77 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.77 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.77 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29651864 | 1.00 | THRB (0.77) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL677617 | 1.00 | THRB (0.77) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL1170063 | 1.00 | THRB (0.77) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL14574802 | 0.90 | THRB (0.70) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL14575018 | 0.90 | THRB (0.70) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL14574800 | 0.90 | THRB (0.70) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL677606 | 0.88 | MEN1 (0.74) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL2139921 | 0.88 | MEN1 (0.74) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL9619480 | 0.88 | MEN1 (0.74) | THRBMEN1KMT2ATHRALMNA | |
| Diiodothyronine SCHEMBL677645 | 0.87 | MEN1 (0.78) | THRBMEN1KMT2ATHRALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117554536-B | Simultaneous analysis method for 15 thyroid hormones in environmental water sample | 北京林业大学 | 2024-03-19 | — | — | CN | claimed |
| CN-117554536-A | Simultaneous analysis method for 15 thyroid hormones in environmental water sample | 北京林业大学 | 2024-02-13 | — | — | CN | claimed |
| CN-114609266-B | Application of marker in preparation of diagnostic reagent for thyroid related diseases | 徐州医科大学 | 2023-03-24 | — | — | CN | disclosed |