Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.57 |
| ▸ | AR | P10275 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30679130 | 1.00 | POLB (0.67) | POLBAKR1C3ALDH1A1L3MBTL1LMNA | |
| SCHEMBL30679121 | 0.90 | MEN1 (0.73) | POLBALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL29134741 | 0.90 | MEN1 (0.73) | POLBALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL29134712 | 0.80 | GAA (0.71) | AKR1C3ALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL30679108 | 0.80 | GAA (0.71) | AKR1C3ALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL664241 | 0.78 | AKR1C3 (1.00) | AKR1C3LMNAMEN1KMT2AHTT | |
| SCHEMBL30679105 | 0.78 | AKR1C3 (1.00) | AKR1C3LMNAMEN1KMT2AHTT | |
| SCHEMBL29135070 | 0.78 | LMNA (0.68) | POLBAKR1C3ALDH1A1L3MBTL1LMNA | |
| SCHEMBL30679109 | 0.78 | LMNA (0.68) | POLBAKR1C3ALDH1A1L3MBTL1LMNA | |
| Thiophene Carboxylic Acid SCHEMBL29135074 | 0.77 | AKR1C3 (0.70) | AKR1C3ALDH1A1LMNAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117298108-A | Androgen receptor and glucocorticoid receptor dual-target inhibitor and application thereof | 浙江师范大学 | 2023-12-29 | — | — | CN | disclosed |