Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.62 |
| ▸ | AR | P10275 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30679106 | 1.00 | L3MBTL1 (0.67) | L3MBTL1AKR1C3NR3C1ARSMN1; SMN2 | |
| SCHEMBL29134746 | 0.90 | MEN1 (0.61) | L3MBTL1SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL30679126 | 0.90 | MEN1 (0.61) | L3MBTL1SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL30679117 | 0.84 | AKR1C3 (0.64) | L3MBTL1AKR1C3NR3C1ARSMN1; SMN2 | |
| SCHEMBL29134722 | 0.84 | AKR1C3 (0.64) | L3MBTL1AKR1C3NR3C1ARSMN1; SMN2 | |
| SCHEMBL29135070 | 0.81 | LMNA (0.68) | L3MBTL1AKR1C3NR3C1ARSMN1; SMN2 | |
| SCHEMBL30679109 | 0.81 | LMNA (0.68) | L3MBTL1AKR1C3NR3C1ARSMN1; SMN2 | |
| SCHEMBL665055 | 0.81 | L3MBTL1 (1.00) | L3MBTL1AKR1C3NR3C1ARSMN1; SMN2 | |
| SCHEMBL30679105 | 0.78 | AKR1C3 (1.00) | AKR1C3NR3C1ARSMN1; SMN2LMNA | |
| SCHEMBL664241 | 0.78 | AKR1C3 (1.00) | AKR1C3NR3C1ARSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117298108-A | Androgen receptor and glucocorticoid receptor dual-target inhibitor and application thereof | 浙江师范大学 | 2023-12-29 | — | — | CN | disclosed |