Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | RIPK1 | Q13546 | 11/20 | 0.75 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30679210 | 1.00 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL29135188 | 1.00 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30679211 | 1.00 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5527901 | 0.85 | POLB (0.82) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL23800951 | 0.79 | RIPK1 (0.65) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL23800957 | 0.78 | RIPK1 (0.71) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9378251 | 0.77 | RIPK1 (0.68) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL23808092 | 0.75 | RIPK1 (0.65) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9676475 | 0.74 | POLB (0.59) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL23830679 | 0.73 | RIPK1 (0.69) | ALDH1A1POLBRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304110-A | Compound and preparation method and application thereof | 宁夏医科大学 | 2023-12-29 | — | — | CN | claimed |
| CN-117304110-A | Compound and preparation method and application thereof | 宁夏医科大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-117304110-A | Compound and preparation method and application thereof | 宁夏医科大学 | 2023-12-29 | — | — | CN | disclosed |