Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RIPK1 | Q13546 | 15/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676868 | 0.89 | POLB (0.58) | POLBRIPK1MAPTMEN1ALDH1A1 | |
| SCHEMBL9678530 | 0.89 | POLB (0.55) | POLBRIPK1MAPTMEN1ALDH1A1 | |
| SCHEMBL9676874 | 0.87 | NPC1 (0.53) | POLBRIPK1MAPTMEN1ALDH1A1 | |
| SCHEMBL9679126 | 0.86 | RIPK1 (0.44) | POLBRIPK1MAPTMEN1ALDH1A1 | |
| SCHEMBL9678564 | 0.85 | POLB (0.57) | POLBRIPK1MAPTMEN1ALDH1A1 | |
| SCHEMBL9677274 | 0.85 | POLB (0.67) | POLBRIPK1MAPTMEN1ALDH1A1 | |
| SCHEMBL9679293 | 0.84 | HTR6 (0.71) | POLBRIPK1MAPTMEN1ALDH1A1 | |
| SCHEMBL9677235 | 0.83 | HTR6 (0.44) | POLBRIPK1MAPTMEN1ALDH1A1 | |
| SCHEMBL9677876 | 0.83 | POLB (0.58) | POLBRIPK1MAPTMEN1ALDH1A1 | |
| SCHEMBL9676149 | 0.82 | POLB (0.64) | POLBRIPK1MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |