SCHEMBL29135216

SCHEMBL29135216

Clc1nccc2ncc(-c3ccccc3)nc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
PDGFRB P09619 1/20 0.46
KDR P35968 1/20 0.46
FLT3 P36888 1/20 0.46
TLR9 Q9NR96 1/20 0.44
ALDH1A1 P00352 1/20 0.43
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
MAPK1 P28482 1/20 0.41
YES1 P07947 2/20 0.41
ABL1 P00519 2/20 0.41
BCHE P06276 1/20 0.40
AURKA O14965 1/20 0.40
HSP90AA1 P07900 1/20 0.40
PRKACA P17612 1/20 0.40
ADORA2A P29274 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30679226 1.00 SMN1; SMN2 (0.47) SMN1; SMN2NPC1RAB9APDGFRBKDR
SCHEMBL15539550 0.87 YES1 (0.50) SMN1; SMN2NPC1RAB9APDGFRBKDR
SCHEMBL30679225 0.87 YES1 (0.50) SMN1; SMN2NPC1RAB9APDGFRBKDR
SCHEMBL30679231 0.87 YES1 (0.50) SMN1; SMN2NPC1RAB9APDGFRBKDR
SCHEMBL30679240 0.80 PARP1 (0.53) SMN1; SMN2NPC1RAB9A
SCHEMBL29135222 0.80 PARP1 (0.53) SMN1; SMN2NPC1RAB9A
SCHEMBL3133009 0.76 YES1 (0.47) SMN1; SMN2NPC1RAB9APDGFRBKDR
SCHEMBL23453506 0.76 FGFR3 (0.58) KDRFLT3MAPK1
SCHEMBL17844934 0.74 ALDH1A1 (0.39) ALDH1A1MAPTMAPK1
SCHEMBL9885994 0.72 MET (0.54) SMN1; SMN2NPC1RAB9APDGFRBKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304233-B Iridium metal complex, application thereof and organic electroluminescent device TSINGHUA UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-117304233-A Iridium metal complex, application thereof and organic electroluminescent device 清华大学 2023-12-29 CN disclosed