Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 10/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29135644 | 1.00 | MKNK2 (0.44) | MKNK2MTNR1AMTNR1BSYKGPR119 | |
| SCHEMBL22916190 | 0.86 | MKNK2 (0.49) | MKNK2MTNR1AMTNR1BSYKGPR119 | |
| SCHEMBL22105276 | 0.85 | MKNK2 (0.48) | MKNK2MTNR1AMTNR1BSYKGPR119 | |
| SCHEMBL22076313 | 0.82 | MKNK2 (0.38) | MKNK2SYKNQO2AAK1 | |
| SCHEMBL22076311 | 0.82 | MKNK2 (0.38) | MKNK2SYKNQO2AAK1 | |
| SCHEMBL29135632 | 0.80 | CA1 (0.47) | NQO2 | |
| SCHEMBL23134476 | 0.80 | MKNK2 (0.44) | MKNK2MTNR1AMTNR1BGPR119EPAS1 | |
| SCHEMBL23134567 | 0.80 | MKNK2 (0.49) | MKNK2MTNR1AMTNR1BGPR119AAK1 | |
| SCHEMBL23134558 | 0.80 | MKNK2 (0.44) | MKNK2MTNR1AMTNR1BGPR119EPAS1 | |
| SCHEMBL29135633 | 0.80 | AAK1 (0.44) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229295-A | Nitrogen-containing macrocyclic compound, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-12-15 | — | — | CN | disclosed |