SCHEMBL29135633

SCHEMBL29135633

CC(COc1ccc(F)cc1COS(C)(=O)=O)NC(=O)OC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 4/20 0.44
PTGER1 P34995 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30786834 1.00 AAK1 (0.44) AAK1PTGER1
SCHEMBL23134655 0.84 AAK1 (0.47) AAK1
SCHEMBL22105203 0.84 AAK1 (0.38) AAK1
SCHEMBL22105193 0.83 SCN9A (0.37) AAK1
SCHEMBL29135695 0.82 CTSS (0.38) AAK1
SCHEMBL29135694 0.82 CTSS (0.38) AAK1
SCHEMBL29135647 0.82 SSTR4 (0.41) AAK1
SCHEMBL29135632 0.80 CA1 (0.47)
SCHEMBL23133871 0.80 AAK1 (0.45) AAK1
SCHEMBL29135641 0.80 MKNK2 (0.44) AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229295-A Nitrogen-containing macrocyclic compound, and preparation method and medical application thereof 中国医药研究开发中心有限公司 2023-12-15 CN disclosed