SCHEMBL29135718

SCHEMBL29135718

C=CC(=O)Oc1ccc2c(c1)C1=C(CC(C)O1)C(=O)C2=O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.53
NQO1 P15559 2/20 0.38
POR P16435 2/20 0.38
MALT1 Q9UDY8 2/20 0.37
THRB P10828 2/20 0.36
CLK1 P49759 1/20 0.33
DYRK1A Q13627 1/20 0.33
DYRK1B Q9Y463 1/20 0.33
MAOA P21397 7/20 0.33
MAOB P27338 3/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29135720 0.99 STAT3 (0.52) STAT3NQO1PORMALT1THRB
SCHEMBL29135593 0.81 STAT3 (0.60) STAT3NQO1PORMALT1CLK1
SCHEMBL29199282 0.76 STAT3 (0.67) STAT3NQO1PORMALT1CLK1
SCHEMBL29135713 0.76 STAT3 (0.53) STAT3MALT1MAOAMAOBIDO1
SCHEMBL29135596 0.74 STAT3 (0.44) STAT3MALT1MAOAMAOBKDM4E
SCHEMBL30662473 0.71 STAT3 (0.52) STAT3NQO1PORMALT1THRB
SCHEMBL29199272 0.71 STAT3 (0.59) STAT3MALT1MAOAMAOBIDO1
SCHEMBL2814971 0.70 TTR (0.46) THRBMAOAALDH1A1MAPTKMT2A
SCHEMBL3329494 0.69 STAT3 (0.49) STAT3NQO1PORMALT1CLK1
SCHEMBL29199273 0.69 STAT3 (1.00) STAT3MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117105894-A Preparation method and application of cryptotanshinone compound 中国人民解放军海军军医大学 2023-11-24 CN disclosed