SCHEMBL3329494

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3327389	0.85	STAT3 (0.50)	STAT3KDM4EALDH1A1HSD17B10NQO1
	SCHEMBL29135593	0.83	STAT3 (0.60)	STAT3KDM4EALDH1A1TSHRHSD17B10
	SCHEMBL29199282	0.83	STAT3 (0.67)	STAT3KDM4EALDH1A1TSHRHSD17B10
	SCHEMBL3334136	0.82	STAT3 (0.43)	STAT3KDM4EALDH1A1HSD17B10MAOB
	SCHEMBL3327381	0.81	DNMT1 (0.50)	STAT3KDM4EALDH1A1HSD17B10MAOB
	SCHEMBL8197108	0.73	TCF4 (0.57)	STAT3KDM4EALDH1A1HSD17B10NQO1
	SCHEMBL3330784	0.70	STAT3 (0.43)	STAT3KDM4EALDH1A1HSD17B10MAOB
	SCHEMBL8047458	0.70	DNMT1 (0.40)	STAT3KDM4EALDH1A1HSD17B10MAOB
	SCHEMBL29135718	0.69	STAT3 (0.53)	STAT3KDM4EALDH1A1CLK1DYRK1A
	SCHEMBL28578515	0.69	KCNJ1 (0.52)	KDM4EALDH1A1CLK1DYRK1ADYRK1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.