Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 3/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30635178 | 1.00 | BRD4 (0.43) | BRD4FFAR1PDGFRBKDRPIK3CD | |
| SCHEMBL29135873 | 0.83 | BRD4 (0.47) | BRD4FFAR1PDGFRBKDRLPL | |
| SCHEMBL30635247 | 0.83 | BRD4 (0.47) | BRD4FFAR1PDGFRBKDRLPL | |
| SCHEMBL29135858 | 0.77 | BRD4 (0.42) | BRD4FFAR1PDGFRBKDRLPL | |
| SCHEMBL30635243 | 0.77 | BRD4 (0.42) | BRD4FFAR1PDGFRBKDRLPL | |
| SCHEMBL2320747 | 0.77 | MKNK1 (0.43) | FFAR1LPLLIPGIRAK4 | |
| SCHEMBL30635222 | 0.76 | BRD4 (0.41) | BRD4FFAR1LPLLIPGIRAK4 | |
| SCHEMBL29135879 | 0.76 | BRD4 (0.41) | BRD4FFAR1LPLLIPGIRAK4 | |
| SCHEMBL21354170 | 0.74 | LPL (0.44) | PDGFRBKDRLPLLIPGIRAK4 | |
| SCHEMBL12373176 | 0.73 | LPL (0.44) | FFAR1LPLLIPGIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050074-A | Pyridine bisimidazopyridine compound and preparation method and application thereof | 中国药科大学 | 2023-11-14 | — | — | CN | disclosed |