Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30635247 | 1.00 | BRD4 (0.47) | BRD4CYP2C19CYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL29135844 | 0.83 | BRD4 (0.43) | BRD4ALDH1A1PRMT5WDR77FFAR1 | |
| SCHEMBL30635178 | 0.83 | BRD4 (0.43) | BRD4ALDH1A1PRMT5WDR77FFAR1 | |
| SCHEMBL17437188 | 0.83 | LPL (0.47) | BRD4CYP2C19CYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL29135845 | 0.74 | BRD4 (0.54) | BRD4CYP2C19CYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL30635213 | 0.74 | BRD4 (0.54) | BRD4CYP2C19CYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL2320747 | 0.73 | MKNK1 (0.43) | FFAR1LPLLIPGTTK | |
| SCHEMBL15730539 | 0.72 | FFAR1 (0.33) | CYP2C19CYP3A4FFAR1CYP1A2CYP2C9 | |
| SCHEMBL30635243 | 0.71 | BRD4 (0.42) | BRD4PRMT5WDR77FFAR1LPL | |
| SCHEMBL29135858 | 0.71 | BRD4 (0.42) | BRD4PRMT5WDR77FFAR1LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050074-A | Pyridine bisimidazopyridine compound and preparation method and application thereof | 中国药科大学 | 2023-11-14 | — | — | CN | disclosed |