Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 17/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537095 | 0.75 | BRD4 (0.58) | CYP1A2CLK4ALDH1A1TSHRMEN1 | |
| SCHEMBL545400 | 0.74 | CYP1A2 (0.43) | CYP1A2CLK4ALDH1A1TSHRMEN1 | |
| SCHEMBL29135884 | 0.73 | BRD4 (0.51) | CYP1A2CLK4TSHRHIF1ACYP2C19 | |
| SCHEMBL29191421 | 0.73 | BRD4 (0.42) | CYP1A2CLK4ALDH1A1TSHRMEN1 | |
| SCHEMBL9657290 | 0.71 | BRD4 (0.62) | BRD4BRD2 | |
| SCHEMBL30231072 | 0.71 | BRD4 (0.49) | CYP1A2CLK4ALDH1A1TSHRMEN1 | |
| SCHEMBL833371 | 0.71 | KDM4E (0.48) | CYP1A2ALDH1A1HIF1ACYP2C19LMNA | |
| SCHEMBL12301359 | 0.70 | CYP1A2 (0.45) | CYP1A2CLK4ALDH1A1TSHRMEN1 | |
| SCHEMBL17055753 | 0.70 | ACHE (0.45) | TSHRMEN1KMT2ALMNA | |
| SCHEMBL18985762 | 0.70 | CYP1A2 (0.48) | CYP1A2CLK4ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050074-A | Pyridine bisimidazopyridine compound and preparation method and application thereof | 中国药科大学 | 2023-11-14 | — | — | CN | disclosed |