SCHEMBL9657290

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12487	0.82	NPC1 (0.69)	BRD4BRD2CREBBPBRD3NPC1
	SCHEMBL16404612	0.79	BRD4 (0.62)	BRD4BRD2CREBBPBRD3NPC1
	SCHEMBL16246450	0.79	BRD4 (0.62)	BRD4BRD2CREBBPBRD3NPC1
	SCHEMBL980536	0.79	MAP4K4 (0.76)	BRD4BRD2CREBBPBRD3NPC1
	SCHEMBL1772573	0.78	BRD4 (0.66)	BRD4BRD2CREBBPBRD3ERN1
	Hydrochloric Acid SCHEMBL1016039	0.78	MAP4K4 (0.73)	BRD4BRD2CREBBPBRD3NPC1
	SCHEMBL5714189	0.78	BRD4 (0.61)	BRD4BRD2CREBBPBRD3NPC1
	3,5-Dimethyl-4-Phenylisoxazole SCHEMBL12134072	0.77	BRD4 (1.00)	BRD4BRD2CREBBP
	SCHEMBL24726640	0.77	BRD4 (0.78)	BRD4BRD2CREBBPBRD3NPC1
	SCHEMBL10145031	0.77	BRD4 (0.59)	BRD4BRD2CREBBPBRD3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.