SCHEMBL29135887

SCHEMBL29135887

NC(=O)c1ccc2ccccc2n1.[Ir]

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.66
ALDH1A1 P00352 4/20 0.62
MAPT P10636 3/20 0.62
GAA P10253 2/20 0.62
CNR2 P34972 6/20 0.59
HDAC8 Q9BY41 1/20 0.59
KDM4E B2RXH2 4/20 0.54
NFKB1 P19838 2/20 0.54
RAB9A P51151 2/20 0.54
NFKB2 Q00653 2/20 0.54
RELA Q04206 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
PIM1 P11309 1/20 0.53
KDM4C Q9H3R0 1/20 0.51
TSHR P16473 2/20 0.50
LMNA P02545 1/20 0.49
MAPK1 P28482 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MEN1 O00255 1/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29540332 0.98 MGAM (0.68) MGAMALDH1A1MAPTGAACNR2
SCHEMBL367913 0.98 MGAM (0.68) MGAMALDH1A1MAPTGAACNR2
SCHEMBL5788458 0.96 MGAM (0.66) MGAMALDH1A1MAPTGAACNR2
Hydrochloric Acid SCHEMBL3401098 0.96 MGAM (0.66) MGAMALDH1A1MAPTGAACNR2
SCHEMBL5788456 0.96 MGAM (0.66) MGAMALDH1A1MAPTGAACNR2
Ammonia Solution, Strong SCHEMBL29239526 0.96 MGAM (0.66) MGAMALDH1A1MAPTGAACNR2
SCHEMBL31434313 0.96 MGAM (0.66) MGAMALDH1A1MAPTGAACNR2
Hydrochloric Acid SCHEMBL3400880 0.96 MGAM (0.66) MGAMALDH1A1MAPTGAACNR2
Thiophene SCHEMBL3425727 0.88 MGAM (0.56) MGAMALDH1A1MAPTGAACNR2
Phthalic Acid SCHEMBL30909153 0.88 MGAM (0.66) MGAMALDH1A1MAPTGAACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117050119-B High-hydrogenation-activity pyrene functionalized amide iridium complex and preparation method thereof 烟台大学 2024-08-23 CN disclosed
CN-117050119-A High-hydrogenation-activity pyrene functionalized amide iridium complex and preparation method thereof 烟台大学 2023-11-14 CN disclosed