Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL27503113 | 1.00 | MGAM (0.66) | MGAMALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29540332 | 0.89 | MGAM (0.68) | MGAMALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL367913 | 0.89 | MGAM (0.68) | MGAMALDH1A1RAB9ASMN1; SMN2NPC1 | |
| Ammonia Solution, Strong SCHEMBL29239526 | 0.88 | MGAM (0.66) | MGAMALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5788456 | 0.88 | MGAM (0.66) | MGAMALDH1A1RAB9ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL3401098 | 0.88 | MGAM (0.66) | MGAMALDH1A1RAB9ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL3400880 | 0.88 | MGAM (0.66) | MGAMALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29135887 | 0.88 | MGAM (0.66) | MGAMALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31434313 | 0.88 | MGAM (0.66) | MGAMALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5788458 | 0.88 | MGAM (0.66) | MGAMALDH1A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |