Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | CNR2 | P34972 | 5/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540332 | 1.00 | MGAM (0.68) | MGAMALDH1A1MAPTGAACNR2 | |
| SCHEMBL5788458 | 0.98 | MGAM (0.66) | MGAMALDH1A1MAPTGAACNR2 | |
| SCHEMBL29135887 | 0.98 | MGAM (0.66) | MGAMALDH1A1MAPTGAACNR2 | |
| Hydrochloric Acid SCHEMBL3401098 | 0.98 | MGAM (0.66) | MGAMALDH1A1MAPTGAACNR2 | |
| SCHEMBL5788456 | 0.98 | MGAM (0.66) | MGAMALDH1A1MAPTGAACNR2 | |
| Ammonia Solution, Strong SCHEMBL29239526 | 0.98 | MGAM (0.66) | MGAMALDH1A1MAPTGAACNR2 | |
| SCHEMBL31434313 | 0.98 | MGAM (0.66) | MGAMALDH1A1MAPTGAACNR2 | |
| Hydrochloric Acid SCHEMBL3400880 | 0.98 | MGAM (0.66) | MGAMALDH1A1MAPTGAACNR2 | |
| Thiophene SCHEMBL3425727 | 0.89 | MGAM (0.56) | MGAMALDH1A1MAPTGAACNR2 | |
| Phthalic Acid SCHEMBL30909153 | 0.89 | MGAM (0.66) | MGAMALDH1A1MAPTGAACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1906 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12371416-B2 | Compounds for inhibition of fibroblast activation protein | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2025-07-29 | — | — | US | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| WO-2025058297-A1 | COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING STAT3 INHIBITOR AND NICLOSAMIDE | 국립암센터 | 2025-03-20 | — | — | WO | claimed |
| CN-119462501-A | Preparation method of 2-quinolinamide compound promoted by acidic ionic liquid | 内蒙古民族大学 | 2025-02-18 | — | — | CN | claimed |
| CN-119390688-A | Quinoline amide derivative, and preparation method and application thereof | 华南农业大学 | 2025-02-07 | — | — | CN | claimed |
| CN-119080882-A | Eptifibatide derivative and preparation method thereof | 山西医科大学 | 2024-12-06 | — | — | CN | claimed |
| CN-118666933-A | Quinoline amide organogelator and preparation method and application thereof | 上海应用技术大学 | 2024-09-20 | — | — | CN | claimed |
| CN-117794896-A | Protease inhibitors for the treatment of coronavirus infections | 斯克里普斯研究学院 | 2024-03-29 | — | — | CN | claimed |
| CN-115197240-B | Quinoline compound, synthesis method, pharmaceutical composition and application | 江南大学 | 2024-03-26 | — | — | CN | claimed |
| EP-3386511-B2 | METHODS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2024-03-20 | — | — | EP | claimed |
| CN-1284878-A | Drugs augmenting NKT cells | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-02-21 | — | — | CN | claimed |
| WO-2000076505-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-12-21 | — | — | WO | claimed |
| WO-2000062792-A2 | COMPOSITIONS AND METHODS FOR CONTROLLING PESTS | INSECT BIOTECHNOLOGY, INC. (US) | 2000-10-26 | — | — | WO | claimed |
| EP-1042295-A1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-11 | — | — | EP | claimed |
| EP-0973767-A1 | INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS | Dupont Pharmaceuticals Company (US) | 2000-01-26 | — | — | EP | claimed |
| US-5985867-A | TREATING HIV INFECTION | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-11-16 | — | — | US | claimed |
| WO-1999032450-A1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-01 | — | — | WO | claimed |
| WO-1998043969-A1 | INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS | DUPONT PHARMACEUTICALS COMPANY (US) | 1998-10-08 | — | — | WO | claimed |
| US-5017636-A | Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-21 | — | — | US | claimed |
| US-4616069-A | REACTING THE ALKALI METAL OR ALKALINE EARTH METAL TERMINATED POLYMER WITH TIN COMPOUND AND ORGANIC COMPOUND HAVING AMIDE OR THIOAMIDE LINKAGES | NIPPON ZEON CO., LTD. (JP) | 1986-10-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371416-B2 | Compounds for inhibition of fibroblast activation protein | FAP, FIBP, APC | MGAM 1756/4885ALDH1A1 1043/4885MAPT 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.