Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | GRK2 | P25098 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27177207 | 1.00 | KMT2A (0.50) | KMT2ATP53GFERGAAHCRTR1 | |
| SCHEMBL29136098 | 0.86 | KMT2A (0.51) | KMT2AGFERGAAHCRTR1 | |
| SCHEMBL27177233 | 0.86 | KMT2A (0.51) | KMT2AGFERGAAHCRTR1 | |
| SCHEMBL28188379 | 0.85 | GFER (0.51) | KMT2AGFERGAA | |
| SCHEMBL4755107 | 0.85 | KMT2A (0.52) | KMT2AGFERGAA | |
| SCHEMBL30775698 | 0.84 | LMNA (0.47) | KMT2ATP53GRK2CASP6CASP8 | |
| SCHEMBL30941590 | 0.83 | USP30 (0.56) | KMT2AGFERL3MBTL1 | |
| SCHEMBL29136112 | 0.83 | USP30 (0.56) | KMT2AGFERL3MBTL1 | |
| SCHEMBL30027279 | 0.81 | KMT2A (0.60) | KMT2AL3MBTL1 | |
| SCHEMBL27177262 | 0.81 | KMT2A (0.49) | KMT2AGFERGAAHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321042-A | Oxodihydro indole compounds for the treatment of inflammatory diseases or cancers | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |