Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | UBE2M | P61081 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136105 | 0.84 | KMT2A (0.50) | TP53GRK2CASP6CASP8CTDSP1 | |
| SCHEMBL27177207 | 0.84 | KMT2A (0.50) | TP53GRK2CASP6CASP8CTDSP1 | |
| SCHEMBL3801054 | 0.83 | SPR (0.50) | TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL4131412 | 0.83 | KDM4E (0.60) | LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL5969516 | 0.83 | EPHX2 (0.54) | LMNAKDM4ECTDSP1TDP1L3MBTL1 | |
| SCHEMBL28206562 | 0.82 | CCR5 (0.49) | MAPTTHRBL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL27167162 | 0.81 | ALDH1A1 (0.62) | LMNAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL30056476 | 0.81 | ALDH1A1 (0.62) | LMNAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL28774927 | 0.80 | MLNR (0.55) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL27712618 | 0.80 | EPHX2 (0.59) | LMNAUBE2MDCUN1D1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355522-A | PKC-theta modulators | 爱智药人工智能有限公司 | 2024-01-05 | — | — | CN | disclosed |