Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.57 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | FPR3 | P25089 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089132 | 1.00 | USP30 (0.57) | USP30ANO1ALDH1A1PARP1NPC1 | |
| SCHEMBL15584615 | 0.89 | USP30 (0.57) | USP30ANO1ALDH1A1PARP1NPC1 | |
| SCHEMBL30941590 | 0.88 | USP30 (0.56) | USP30ANO1ALDH1A1PARP1NPC1 | |
| SCHEMBL29136112 | 0.88 | USP30 (0.56) | USP30ANO1ALDH1A1PARP1NPC1 | |
| SCHEMBL3003635 | 0.88 | ANO1 (0.56) | USP30ANO1ALDH1A1PARP1NPC1 | |
| SCHEMBL15644901 | 0.87 | USP30 (0.62) | USP30ALDH1A1PARP1NPC1MAPT | |
| SCHEMBL20970042 | 0.87 | USP30 (0.62) | USP30ALDH1A1PARP1NPC1MAPT | |
| SCHEMBL15644903 | 0.87 | USP30 (0.62) | USP30ALDH1A1PARP1NPC1MAPT | |
| SCHEMBL18937875 | 0.86 | ALDH1A1 (0.57) | USP30ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL24781306 | 0.86 | KMT2A (0.59) | USP30ANO1MAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321042-A | Oxodihydro indole compounds for the treatment of inflammatory diseases or cancers | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |