Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.56 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.56 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089132 | 0.88 | USP30 (0.57) | ANO1USP30ALDH1A1NPC1MAPT | |
| SCHEMBL29136107 | 0.88 | USP30 (0.57) | ANO1USP30ALDH1A1NPC1MAPT | |
| SCHEMBL15584615 | 0.88 | USP30 (0.57) | ANO1USP30ALDH1A1NPC1MAPT | |
| SCHEMBL29136112 | 0.87 | USP30 (0.56) | ANO1USP30ALDH1A1NPC1MAPT | |
| SCHEMBL30941590 | 0.87 | USP30 (0.56) | ANO1USP30ALDH1A1NPC1MAPT | |
| SCHEMBL16764325 | 0.87 | ANO1 (0.57) | ANO1USP30STSCNR1CNR2 | |
| SCHEMBL16764326 | 0.87 | ANO1 (0.57) | ANO1USP30STSCNR1CNR2 | |
| SCHEMBL13434252 | 0.86 | ALDH1A1 (0.58) | ANO1USP30STSCNR1CNR2 | |
| SCHEMBL20970042 | 0.86 | USP30 (0.62) | USP30ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL15644901 | 0.86 | USP30 (0.62) | USP30ALDH1A1NPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190829-A1 | RENIN INHIBITORS | VITAE PHARMACEUTICALS INC | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190829-A1 | RENIN INHIBITORS | ACE, REN, DNPEP | ANO1 3928/4885USP30 684/4885STS 1946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.