Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.50 |
| ▸ | FPR2 | P25090 | 4/20 | 0.48 |
| ▸ | FPR3 | P25089 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12607070 | 0.88 | PRMT5 (0.56) | PRMT5WDR77JAK2JAK1USP30 | |
| SCHEMBL29117319 | 0.88 | PRMT5 (0.56) | PRMT5WDR77JAK2JAK1USP30 | |
| SCHEMBL12607067 | 0.88 | PRMT5 (0.56) | PRMT5WDR77JAK2JAK1USP30 | |
| SCHEMBL17274387 | 0.88 | USP30 (0.47) | PRMT5WDR77FPR2FPR3CACNA1B | |
| SCHEMBL3343608 | 0.86 | GPR119 (0.52) | PRMT5WDR77FPR2DDB1CRBN | |
| SCHEMBL2069058 | 0.86 | MEN1 (0.48) | PRMT5WDR77CACNA1BDDB1CRBN | |
| SCHEMBL4469145 | 0.84 | DRD4 (0.53) | PRMT5WDR77PDE4B | |
| SCHEMBL27471148 | 0.83 | PRMT5 (0.52) | PRMT5WDR77JAK2JAK1PDE4B | |
| SCHEMBL29964707 | 0.82 | CHEK2 (0.55) | PRMT5WDR77FPR2FPR3MEN1 | |
| SCHEMBL29964863 | 0.82 | CHEK2 (0.55) | PRMT5WDR77FPR2FPR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321042-A | Oxodihydro indole compounds for the treatment of inflammatory diseases or cancers | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |