Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201646 | 0.86 | RECQL (0.44) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3079067 | 0.83 | P2RX4 (0.44) | RAB9AHTR3AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3086229 | 0.83 | CYP1A2 (0.39) | RAB9APOLBKDM4E | |
| SCHEMBL29136204 | 0.83 | HTT (0.45) | RAB9AALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL29136191 | 0.80 | MAPT (0.40) | HTR3AALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL3088019 | 0.80 | ALOX5AP (0.42) | RAB9AALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL3091129 | 0.80 | P2RX4 (0.48) | RAB9AHTR3AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3079977 | 0.80 | DRD2 (0.41) | ALDH1A1HTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL29136197 | 0.75 | KDM4E (0.44) | RAB9AHTR3AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL15271285 | 0.74 | RECQL (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003739-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 安徽中医药大学 | 2023-11-07 | — | — | CN | disclosed |