Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136196 | 0.92 | MAPT (0.43) | KDM4ELMNACYP2C9TSHRMAPT | |
| SCHEMBL29136185 | 0.82 | CCR2 (0.52) | KDM4EMAPTALDH1A1POLBKMT2A | |
| SCHEMBL29136191 | 0.80 | MAPT (0.40) | MAPTHTR3EHTR3BHTR1AHTR3A | |
| SCHEMBL28995440 | 0.79 | CYP19A1 (0.40) | KDM4ELMNANPSR1MAPTHTR1A | |
| SCHEMBL3091129 | 0.77 | P2RX4 (0.48) | KDM4ELMNANPSR1MAPTHTR3A | |
| SCHEMBL29136199 | 0.76 | CCR2 (0.55) | KDM4ELMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5894379 | 0.76 | HDAC8 (0.56) | KDM4ELMNANPSR1CYP1A2CYP3A4 | |
| SCHEMBL29136188 | 0.75 | RAB9A (0.42) | KDM4ELMNANPSR1TSHRMAPT | |
| SCHEMBL28415278 | 0.74 | DCTPP1 (0.41) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29136202 | 0.71 | KMT2A (0.55) | KDM4ELMNATSHRMAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003739-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 安徽中医药大学 | 2023-11-07 | — | — | CN | disclosed |