SCHEMBL29136233

SCHEMBL29136233

CC(O)COC(=O)c1ccccc1C(N)=O

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.64
ALDH1A1 P00352 4/20 0.64
CYP3A4 P08684 2/20 0.48
CA2 P00918 1/20 0.48
IRAK4 Q9NWZ3 1/20 0.47
ADRB2 P07550 6/20 0.47
ADRB1 P08588 6/20 0.47
ADRB3 P13945 6/20 0.47
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
HTT P42858 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HSD17B10 Q99714 1/20 0.44
TP53 P04637 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8466969 0.91 TSHR (0.75) TSHRALDH1A1CYP3A4CA2ADRB2
SCHEMBL9104304 0.88 TSHR (0.66) TSHRALDH1A1CYP3A4CA2ADRB2
SCHEMBL28228886 0.85 ALDH1A1 (0.66) TSHRALDH1A1CYP3A4CA2ADRB2
SCHEMBL18411635 0.85 TSHR (0.66) TSHRALDH1A1CYP3A4CA2ADRB2
SCHEMBL28757476 0.85 TSHR (0.72) TSHRALDH1A1CYP3A4CA2ADRB2
SCHEMBL10591909 0.85 TSHR (0.66) TSHRALDH1A1CYP3A4CA2ADRB2
SCHEMBL30306347 0.85 ALDH1A1 (0.66) TSHRALDH1A1CYP3A4CA2ADRB2
SCHEMBL31036163 0.85 TSHR (0.72) TSHRALDH1A1CYP3A4CA2ADRB2
SCHEMBL4597929 0.85 ALDH1A1 (0.66) TSHRALDH1A1CYP3A4CA2ADRB2
SCHEMBL20432946 0.82 TSHR (0.62) TSHRALDH1A1CYP3A4CA2ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117003980-A Polyol composition, polyurethane hard foam and preparation method thereof 红宝丽集团股份有限公司 2023-11-07 CN disclosed