Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727622 | 0.80 | NOS3 (0.48) | NOS3NOS1NOS2MAPTALDH1A1 | |
| SCHEMBL6280564 | 0.74 | IDO1 (0.43) | NOS3NOS1NOS2IDO1MAPT | |
| SCHEMBL15691394 | 0.74 | IDO1 (0.35) | IDO1MAPTALDH1A1KMT2A | |
| SCHEMBL16792339 | 0.74 | IDO1 (0.35) | IDO1MAPTALDH1A1KMT2A | |
| SCHEMBL19454605 | 0.74 | IDO1 (0.35) | IDO1MAPT | |
| SCHEMBL17501010 | 0.71 | IDO1 (0.33) | IDO1 | |
| SCHEMBL11736946 | 0.71 | NOS3 (0.40) | NOS3NOS1NOS2 | |
| SCHEMBL82917 | 0.71 | — | — | |
| SCHEMBL15165635 | 0.70 | L3MBTL1 (0.36) | NOS2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL19434344 | 0.69 | SMN1; SMN2 (0.50) | POLBMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343056-A | Pyridopyrrole derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-01-05 | — | — | CN | disclosed |