Morpholine

Morpholine

SCHEMBL29136408

C1COCCN1.CC(=O)N1CCOCC1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.72
HTT P42858 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
GAA P10253 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP2C9 P11712 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TSHR P16473 1/20 0.41
MMP1 P03956 1/20 0.41
MMP3 P08254 1/20 0.41
MMP8 P22894 1/20 0.41
MAPT P10636 1/20 0.40
USP2 O75604 1/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7742546 0.92 SMN1; SMN2 (0.72) SMN1; SMN2HTTMEN1KMT2AGAA
SCHEMBL2187341 0.87
SCHEMBL4236 0.87
SCHEMBL13173709 0.84 SMN1; SMN2 (1.00) SMN1; SMN2HTTMEN1KMT2AGAA
SCHEMBL13921120 0.84 SMN1; SMN2 (1.00) SMN1; SMN2HTTMEN1KMT2AGAA
SCHEMBL19985902 0.84 SMN1; SMN2 (1.00) SMN1; SMN2HTTMEN1KMT2AGAA
Hydrochloric Acid SCHEMBL5485891 0.84 SMN1; SMN2 (0.90) SMN1; SMN2HTTMEN1KMT2AGAA
Morpholine SCHEMBL27737341 0.79 GAA (0.61) SMN1; SMN2HTTMEN1KMT2AGAA
Morpholine SCHEMBL11737913 0.79 KDM4E (0.44) SMN1; SMN2HTTMEN1KMT2AGAA
SCHEMBL12409426 0.78 SMN1; SMN2 (0.78) SMN1; SMN2HTTMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117321150-A Corrosion inhibiting coating composition PRC-迪索托国际公司 2023-12-29 CN claimed