SCHEMBL7742546

SCHEMBL7742546

CC(=O)N1CCNCC1.CC(=O)N1CCOCC1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.72
HTT P42858 1/20 0.46
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA9 Q16790 2/20 0.43
CA2 P00918 2/20 0.43
CHKA P35790 1/20 0.42
MEN1 O00255 1/20 0.42
TP53 P04637 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP1A2 P05177 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TSHR P16473 1/20 0.41
MMP1 P03956 1/20 0.41
MMP3 P08254 1/20 0.41
MMP8 P22894 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA4 P43681 1/20 0.41
CHRNB3 Q05901 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL29136408 0.92 SMN1; SMN2 (0.72) SMN1; SMN2HTTCA12CA1CA9
SCHEMBL603099 0.87
SCHEMBL2187341 0.87
SCHEMBL5433 0.87
SCHEMBL4236 0.87
SCHEMBL13173709 0.84 SMN1; SMN2 (1.00) SMN1; SMN2HTTCA12CA1CA9
SCHEMBL15689312 0.84 CA2 (0.52) SMN1; SMN2CA12CA1CA9CA2
SCHEMBL13921120 0.84 SMN1; SMN2 (1.00) SMN1; SMN2HTTCA12CA1CA9
Hydrochloric Acid SCHEMBL5485891 0.84 SMN1; SMN2 (0.90) SMN1; SMN2HTTCA12CA1CA9
SCHEMBL9286350 0.84 CA2 (0.52) SMN1; SMN2CA12CA1CA9CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6429282-B1 MIXING PRIMARY AND SECONDARY AMINES WITH EMERALDINE BASE POLYANILINE; STORAGE STABILITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-08-06 US claimed