Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829544 | 0.86 | TOP2A (0.53) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL25400139 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4ECYP2C19HTTKMT2A | |
| SCHEMBL28326425 | 0.83 | ALDH1A1 (0.45) | ALDH1A1POLBCA12CA7CA14 | |
| SCHEMBL13948837 | 0.81 | MAPT (0.60) | ALDH1A1KDM4EPOLBGLACA12 | |
| SCHEMBL19974750 | 0.81 | CHRM2 (0.57) | ALDH1A1POLBCA12CA7CA14 | |
| SCHEMBL29577048 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBCA12CA9 | |
| SCHEMBL6090937 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBCA12CA9 | |
| SCHEMBL10875175 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBGLACA12 | |
| SCHEMBL23291793 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EPOLBGLACA12 | |
| SCHEMBL7746507 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBGLACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294806-A1 | TYK2 INHIBITORS AND USES THEREOF | Sudo Biosciences Limited (GB) | 2023-12-27 | — | — | EP | disclosed |
| CN-117120440-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022175746-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-08-25 | — | — | WO | disclosed |