Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.72 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.69 |
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | FBP1 | P09467 | 2/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405433 | 1.00 | CYP19A1 (0.72) | CYP19A1NFE2L2APPRAB9ANPC1 | |
| SCHEMBL1405432 | 1.00 | CYP19A1 (0.72) | CYP19A1NFE2L2APPRAB9ANPC1 | |
| Dimethylamine SCHEMBL5514324 | 0.92 | CYP19A1 (0.64) | CYP19A1NFE2L2APPRAB9ANPC1 | |
| SCHEMBL14947048 | 0.91 | APP (0.78) | CYP19A1NFE2L2APPRAB9ANPC1 | |
| SCHEMBL458178 | 0.91 | APP (0.78) | CYP19A1NFE2L2APPRAB9ANPC1 | |
| SCHEMBL9170804 | 0.91 | APP (0.78) | CYP19A1NFE2L2APPRAB9ANPC1 | |
| SCHEMBL458177 | 0.91 | APP (0.78) | CYP19A1NFE2L2APPRAB9ANPC1 | |
| SCHEMBL9170800 | 0.91 | APP (0.78) | CYP19A1NFE2L2APPRAB9ANPC1 | |
| SCHEMBL28471601 | 0.91 | CYP19A1 (0.62) | CYP19A1NFE2L2APPRAB9ANPC1 | |
| SCHEMBL592401 | 0.90 | APP (0.85) | CYP19A1NFE2L2APPRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676926-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS | ThirtyFiveBio Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184650-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS. | ThirtyFiveBio Limited (GB) | 2024-09-12 | — | — | WO | disclosed |
| CN-117362160-A | Synthesis method of stilbene derivative Z-configuration isomer | 广东克冠达医药科技有限公司 | 2024-01-09 | — | — | CN | disclosed |