SCHEMBL29136545

SCHEMBL29136545

NC(=O)c1cccc(S)c1S

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HDAC8 Q9BY41 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
METAP2 P50579 1/20 0.43
GAA P10253 1/20 0.42
BCAT2 O15382 1/20 0.42
PARP1 P09874 8/20 0.41
IRAK4 Q9NWZ3 1/20 0.41
PDPK1 O15530 1/20 0.41
AURKA O14965 2/20 0.39
PLK4 O00444 1/20 0.39
CHEK1 O14757 1/20 0.39
DAPK3 O43293 1/20 0.39
MAP4K4 O95819 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL477978 0.81 MAPT (0.62) MAPTKDM4EALDH1A1HDAC8HPGD
SCHEMBL31475293 0.81 MAPT (0.62) MAPTKDM4EALDH1A1HDAC8HPGD
SCHEMBL7908528 0.80 PARP1 (0.46) MAPTKDM4EALDH1A1HPGDTSHR
SCHEMBL30786246 0.80 PARP1 (0.46) MAPTKDM4EALDH1A1HPGDTSHR
SCHEMBL28952367 0.80 MAPT (0.45) MAPTKDM4EALDH1A1HDAC8HPGD
Hydrogen Sulfide SCHEMBL8218033 0.79 MAPT (0.60) MAPTKDM4EALDH1A1HDAC8HPGD
SCHEMBL8511204 0.79 MAPT (0.67) MAPTKDM4EALDH1A1HDAC8HPGD
SCHEMBL27896832 0.79 MAPT (0.60) MAPTKDM4EALDH1A1HDAC8HPGD
Methane SCHEMBL28001772 0.79 MAPT (0.60) MAPTKDM4EALDH1A1HDAC8HPGD
SCHEMBL27914301 0.79 MAPT (0.60) MAPTKDM4EALDH1A1HDAC8HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362209-A Method for preparing N-dimercaptobenzamide and derivatives thereof by photocatalysis 上海陶术生物科技有限公司 2024-01-09 CN claimed
CN-117362209-A Method for preparing N-dimercaptobenzamide and derivatives thereof by photocatalysis 上海陶术生物科技有限公司 2024-01-09 CN disclosed
CN-117362209-A Method for preparing N-dimercaptobenzamide and derivatives thereof by photocatalysis 上海陶术生物科技有限公司 2024-01-09 CN disclosed
CN-117362209-A Method for preparing N-dimercaptobenzamide and derivatives thereof by photocatalysis 上海陶术生物科技有限公司 2024-01-09 CN disclosed