SCHEMBL477978

SCHEMBL477978

NC(=O)c1ccccc1S

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.62
HDAC8 Q9BY41 1/20 0.62
ALDH1A1 P00352 5/20 0.56
KDM4E B2RXH2 3/20 0.56
TSHR P16473 2/20 0.56
HSD17B10 Q99714 2/20 0.56
HPGD P15428 2/20 0.56
METAP2 P50579 1/20 0.52
BCAT2 O15382 1/20 0.50
IRAK4 Q9NWZ3 1/20 0.48
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
GAA P10253 1/20 0.45
CTNNB1 P35222 1/20 0.45
SIRT1 Q96EB6 1/20 0.45
POLB P06746 1/20 0.44
CYP3A4 P08684 1/20 0.44
PARP1 P09874 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31475293 1.00 MAPT (0.62) MAPTHDAC8ALDH1A1KDM4ETSHR
Methane SCHEMBL28001772 0.98 MAPT (0.60) MAPTHDAC8ALDH1A1KDM4ETSHR
Hydrogen Sulfide SCHEMBL8218033 0.98 MAPT (0.60) MAPTHDAC8ALDH1A1KDM4ETSHR
SCHEMBL27914301 0.98 MAPT (0.60) MAPTHDAC8ALDH1A1KDM4ETSHR
SCHEMBL27896832 0.98 MAPT (0.60) MAPTHDAC8ALDH1A1KDM4ETSHR
SCHEMBL14890168 0.83 ALDH1A1 (0.66) MAPTHDAC8ALDH1A1KDM4ETSHR
Thiosalicylic Acid SCHEMBL28479129 0.81 MAPT (0.86) MAPTHDAC8ALDH1A1KDM4ETSHR
SCHEMBL29136545 0.81 MAPT (0.46) MAPTHDAC8ALDH1A1KDM4ETSHR
SCHEMBL39118 0.81 ALDH1A1 (0.70) MAPTALDH1A1KDM4ETSHRHSD17B10
SCHEMBL4967588 0.81 ALDH1A1 (0.70) MAPTALDH1A1KDM4ETSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119799342-A Efficient soil heavy metal solidification stabilization medicament and preparation method thereof 天津宏福艺源环保科技有限公司 2025-04-11 CN claimed
CN-118063402-A Synthesis process of saccharin 上海交通大学 2024-05-24 CN claimed
US-20230312809-A1 LIQUID FORMULATION COMPRISING AN ALDEHYDE SCAVENGER Ferline SA (CH) 2023-10-05 US claimed
US-20230257746-A1 TARGETING ZNF410 FOR FETAL HEMOGLOBIN INDUCTION IN BETAHEMOGLOBINOPATHIES THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2023-08-17 US claimed
CN-115253611-B Mixed matrix membrane CO accurately regulated and controlled by using specific surface area of filler 2 Method for separating properties 大连理工大学盘锦产业技术研究院 2023-05-26 CN claimed
EP-4182445-A2 TARGETING ZNF410 FOR FETAL HEMOGLOBIN INDUCTION IN BETA-HEMOGLOBINOPATHIES The Children's Medical Center Corporation (US) 2023-05-24 EP claimed
CN-114181169-B Method for preparing N- (substituent) benzothiazine-4-ketone without participation of metal 常州大学 2023-04-11 CN claimed
EP-4157915-A1 LIQUID FORMULATION COMPRISING AN ALDEHYDE SCAVENGER Ferline SA (CH) 2023-04-05 EP claimed
CN-114181168-B Method for preparing N- (substituent) -2-substituent benzothiazine-4-ketone 常州大学 2023-03-21 CN claimed
CN-115698118-A Liquid formulations comprising aldehyde scavengers 佛莱恩股份公司 2023-02-03 CN claimed
EP-1392767-A1 METHOD TO DECREASE ALDEHYDE CONTENT IN POLYOLEFIN PRODUCTS The Coca-Cola Company (US) 2004-03-03 EP claimed
US-6632874-B2 Reacting aldehyde with a compound such as anthranilamide or 3,4-diaminobenzoic acid to form a condensed ring; for food and beverage containers: no off-taste or discoloration THE COCA-COLA COMPANY 2003-10-14 US claimed
WO-2003080702-A1 POLYTRIMETHYLENE TEREPHTHALATE RESINS WITH IMPROVED PROPERTIES ZIMMER AG (DE) 2003-10-02 WO claimed
EP-1347005-A1 Polytrimethylene terephtalate resins with improved properties Zimmer AG (DE) 2003-09-24 EP claimed
US-20020193481-A1 Method to decrease aldehyde content in polyolefin products COCA-COLA COMPANY, THE 2002-12-19 US claimed
EP-1263880-A2 METHOD TO DECREASE THE ACETALDEHYDE CONTENT OF MELT-PROCESSED POLYESTERS THE COCA-COLA COMPANY (US) 2002-12-11 EP claimed
WO-2002088237-A1 METHOD TO DECREASE ALDEHYDE CONTENT IN POLYOLEFIN PRODUCTS THE COCA-COLA COMPANY (US) 2002-11-07 WO claimed
WO-2001062838-A2 METHOD TO DECREASE THE ACETALDEHYDE CONTENT OF MELT-PROCESSED POLYESTERS THE COCA-COLA COMPANY (US) 2001-08-30 WO claimed
US-6274212-B1 COMBINING WITH MELTED POLYESTER AN ORGANIC ADDITIVE COMPOUND COMPRISING HETEROATOMS WHICH SCAVENGES ACETALDEHYDE FROM THE POLYESTER WITHOUT IMPARTING DISCOLORATION TO POLYESTER THE COCA-COLA COMPANY 2001-08-14 US claimed
EP-0124476-A1 Carboxamides, process for their preparation and pharmaceutical preparations containing them CIBA-GEIGY AG (CH) 1984-11-07 EP claimed