Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477978 | 1.00 | MAPT (0.62) | MAPTHDAC8ALDH1A1KDM4ETSHR | |
| Methane SCHEMBL28001772 | 0.98 | MAPT (0.60) | MAPTHDAC8ALDH1A1KDM4ETSHR | |
| Hydrogen Sulfide SCHEMBL8218033 | 0.98 | MAPT (0.60) | MAPTHDAC8ALDH1A1KDM4ETSHR | |
| SCHEMBL27914301 | 0.98 | MAPT (0.60) | MAPTHDAC8ALDH1A1KDM4ETSHR | |
| SCHEMBL27896832 | 0.98 | MAPT (0.60) | MAPTHDAC8ALDH1A1KDM4ETSHR | |
| SCHEMBL14890168 | 0.83 | ALDH1A1 (0.66) | MAPTHDAC8ALDH1A1KDM4ETSHR | |
| Thiosalicylic Acid SCHEMBL28479129 | 0.81 | MAPT (0.86) | MAPTHDAC8ALDH1A1KDM4ETSHR | |
| SCHEMBL29136545 | 0.81 | MAPT (0.46) | MAPTHDAC8ALDH1A1KDM4ETSHR | |
| SCHEMBL39118 | 0.81 | ALDH1A1 (0.70) | MAPTALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL4967588 | 0.81 | ALDH1A1 (0.70) | MAPTALDH1A1KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |