Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 3/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136621 | 0.84 | AGTR1 (0.55) | TLR7AGTR1AGTR2 | |
| SCHEMBL9214231 | 0.81 | AGTR1 (0.66) | TLR7AGTR1AGTR2POLBHDAC1 | |
| SCHEMBL10593221 | 0.78 | LPO (0.58) | LPOKDM4EALDH1A1GAALMNA | |
| SCHEMBL11014930 | 0.77 | AGTR1 (0.61) | AGTR1AGTR2ALDH1A1POLBHDAC1 | |
| SCHEMBL13720528 | 0.76 | TP53 (0.59) | LPOALDH1A1LMNATP53MAPT | |
| SCHEMBL11013827 | 0.76 | AGTR1 (0.60) | AGTR1AGTR2ALDH1A1POLBHDAC1 | |
| SCHEMBL29037510 | 0.76 | AGTR1 (0.57) | TLR7AGTR1AGTR2HDAC1 | |
| SCHEMBL5291955 | 0.76 | AGTR1 (0.60) | AGTR1AGTR2ALDH1A1POLBHDAC1 | |
| SCHEMBL11046427 | 0.76 | HDAC1 (0.46) | AGTR1AGTR2ALDH1A1POLBHDAC1 | |
| Hydrochloric Acid SCHEMBL28122561 | 0.75 | AGTR1 (0.59) | AGTR1AGTR2ALDH1A1POLBHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355341-A | TLR7 and TLR8 agonists for the treatment of cancer and/or infectious diseases | 纽约州立大学研究基金会 | 2024-01-05 | — | — | CN | disclosed |