Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | RHOA | P61586 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117108 | 0.88 | KMT2A (0.50) | MAOBKMT2AMEN1MAPTRHOA | |
| SCHEMBL22117109 | 0.88 | KMT2A (0.50) | MAOBKMT2AMEN1MAPTRHOA | |
| SCHEMBL29302331 | 0.82 | ALDH1A1 (0.44) | MAOBMAOAKMT2AMEN1MAPT | |
| SCHEMBL29136916 | 0.82 | ALDH1A1 (0.44) | MAOBMAOAKMT2AMEN1MAPT | |
| SCHEMBL29880084 | 0.82 | ALDH1A1 (0.44) | MAOBMAOAKMT2AMEN1MAPT | |
| SCHEMBL1251511 | 0.80 | HDAC3 (0.52) | MAOBKMT2AMEN1MAPTTDP1 | |
| SCHEMBL1251510 | 0.80 | HDAC3 (0.52) | MAOBKMT2AMEN1MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL6818359 | 0.79 | HDAC3 (0.50) | MAOBKMT2AMEN1MAPTTDP1 | |
| SCHEMBL16952819 | 0.78 | ALDH1A1 (0.46) | MAOBMAOAKMT2AMEN1TDP1 | |
| SCHEMBL2537590 | 0.75 | ALDH1A1 (0.47) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |