Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29302331 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1HSP90AA1HPGD | |
| SCHEMBL29880084 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1HSP90AA1HPGD | |
| SCHEMBL6841707 | 0.90 | MAPT (0.49) | ALDH1A1MAPTMEN1HSP90AA1HPGD | |
| SCHEMBL6841705 | 0.90 | MAPT (0.49) | ALDH1A1MAPTMEN1HSP90AA1HPGD | |
| SCHEMBL6821853 | 0.83 | CA12 (0.55) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL6821855 | 0.83 | CA12 (0.55) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL26600131 | 0.83 | PTGS1 (0.55) | ALDH1A1MAPTMEN1HSP90AA1HPGD | |
| SCHEMBL17083190 | 0.83 | MAPT (0.44) | ALDH1A1MAPTMEN1HSP90AA1HPGD | |
| SCHEMBL29136791 | 0.82 | PLA2G4A (0.47) | ALDH1A1MAPTMEN1KMT2ATRPV1 | |
| SCHEMBL1284480 | 0.78 | TRPV1 (0.62) | ALDH1A1MAPTMEN1HSP90AA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |