Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | GBA1 | P04062 | 1/20 | 0.62 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.60 |
| ▸ | METAP1 | P53582 | 1/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912538 | 0.89 | ABCG2 (0.68) | ABCG2MAPTLMNAABCB1KDM4E | |
| SCHEMBL9937654 | 0.86 | ABCG2 (0.77) | ABCG2MAPTLMNAABCB1KDM4E | |
| SCHEMBL22201364 | 0.82 | ABCG2 (0.94) | ABCG2MAPTLMNATP53ABCB1 | |
| SCHEMBL8095812 | 0.82 | ABCG2 (1.00) | ABCG2MAPTLMNATP53ABCB1 | |
| SCHEMBL4470574 | 0.81 | KMT2A (0.64) | ABCG2MAPTLMNAABCB1KDM4E | |
| SCHEMBL1083796 | 0.80 | KDM4E (1.00) | ABCG2MAPTLMNATP53ABCB1 | |
| SCHEMBL5531993 | 0.79 | ABCG2 (0.89) | ABCG2MAPTLMNATP53ABCB1 | |
| SCHEMBL1083802 | 0.79 | MEN1 (0.81) | ABCG2MAPTLMNATP53KDM4E | |
| SCHEMBL14084544 | 0.76 | NPY5R (0.59) | ABCG2MAPTLMNATP53KDM4E | |
| SCHEMBL8093527 | 0.76 | ABCG2 (0.82) | ABCG2MAPTLMNATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966184-B1 | PYRIDINYL-QUINAZOLINE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH AS (DK) | 2010-08-25 | — | — | EP | disclosed |
| US-20090306102-A1 | 2-PYRIDIN-2-YL-QUINAZOLINE DERIVATIVES AS POTASSIUM CHANNEL MODULATING AGENTS FOR THE TREATMENT OF RESPIRATORY DISEASES | NEUROSEARCH A/S (DK) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306102-A1 | 2-PYRIDIN-2-YL-QUINAZOLINE DERIVATIVES AS POTASSIUM CHANNEL MODULATING AGENTS FOR THE TREATMENT OF RESPIRATORY DISEASES | KCNJ2, KCNQ1, KCNK2 | ABCG2 1586/4885MAPT 2920/4885LMNA 1262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.