Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 14/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136982 | 1.00 | KLKB1 (0.42) | KLKB1DGAT1METTL3LRRK2 | |
| SCHEMBL29879679 | 1.00 | KLKB1 (0.42) | KLKB1DGAT1METTL3LRRK2 | |
| SCHEMBL29304970 | 1.00 | KLKB1 (0.42) | KLKB1DGAT1METTL3LRRK2 | |
| SCHEMBL29136881 | 1.00 | KLKB1 (0.42) | KLKB1DGAT1METTL3LRRK2 | |
| SCHEMBL24737770 | 0.94 | METTL3 (0.43) | KLKB1METTL3 | |
| SCHEMBL29305492 | 0.94 | METTL3 (0.43) | KLKB1METTL3 | |
| SCHEMBL29136748 | 0.92 | KDM4E (0.42) | METTL3LRRK2 | |
| SCHEMBL29136745 | 0.92 | KDM4E (0.42) | METTL3LRRK2 | |
| SCHEMBL24738299 | 0.92 | KDM4E (0.42) | METTL3LRRK2 | |
| SCHEMBL24737784 | 0.90 | KLKB1 (0.42) | KLKB1DGAT1METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |