Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607 | 0.82 | KMT2A (0.43) | KMT2AATMALDH1A1PKMSLC1A2 | |
| SCHEMBL43958 | 0.73 | ALDH1A1 (0.38) | KMT2AATMALDH1A1PKMSLC1A2 | |
| SCHEMBL2283238 | 0.73 | ALDH1A1 (0.38) | KMT2AATMALDH1A1PKMSLC1A2 | |
| SCHEMBL1564210 | 0.72 | KMT2A (0.47) | KMT2AATMALDH1A1PKMSLC1A2 | |
| SCHEMBL3801263 | 0.71 | KMT2A (0.46) | KMT2AATMALDH1A1PKMSLC1A2 | |
| SCHEMBL10980060 | 0.70 | KMT2A (0.38) | KMT2AATMALDH1A1PKMSLC1A2 | |
| SCHEMBL604671 | 0.68 | ALDH1A1 (0.56) | KMT2AATMALDH1A1PKMSLC1A2 | |
| SCHEMBL2332165 | 0.68 | ALDH1A1 (0.56) | KMT2AATMALDH1A1PKMSLC1A2 | |
| SCHEMBL3487387 | 0.68 | KMT2A (0.44) | KMT2AATMALDH1A1PKMSLC1A2 | |
| SCHEMBL7754082 | 0.68 | CYP2D6 (0.30) | ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4388014-A1 | MULTIVALENT ANTI-VARIANT FC-REGION ANTIBODIES AND METHODS OF USE | F. Hoffmann-La Roche AG (CH) | 2024-06-26 | — | — | EP | claimed |
| CN-117858905-A | Multivalent anti-variant FC region antibodies and methods of use | 豪夫迈·罗氏有限公司 | 2024-04-09 | — | — | CN | claimed |
| WO-2023021055-A1 | MULTIVALENT ANTI-VARIANT FC-REGION ANTIBODIES AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2023-02-23 | — | — | WO | claimed |
| EP-4388014-A1 | MULTIVALENT ANTI-VARIANT FC-REGION ANTIBODIES AND METHODS OF USE | F. Hoffmann-La Roche AG (CH) | 2024-06-26 | — | — | EP | disclosed |
| CN-117858905-A | Multivalent anti-variant FC region antibodies and methods of use | 豪夫迈·罗氏有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-116196434-A | Antibody-drug conjugate, preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| WO-2023021055-A1 | MULTIVALENT ANTI-VARIANT FC-REGION ANTIBODIES AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2023-02-23 | — | — | WO | disclosed |
| US-9933433-B2 | Anti-drug antibody assay | HOFFMANN-LA ROCHE INC. (US) | 2018-04-03 | — | — | US | disclosed |
| EP-2089434-B1 | ANTI-IDIOTYPE CONJUGATE AND ITS USE AS A STANDARD IN AN IMMUNASSAY | HOFFMANN LA ROCHE (CH) | 2015-12-30 | — | — | EP | disclosed |
| US-20140349323-A1 | ANTI-DRUG ANTIBODY ASSAY | F. HOFFMANN-LA ROCHE AG (CH) | 2014-11-27 | — | — | US | disclosed |
| US-8809005-B2 | Conjugate and its use as a standard in an immunoassay | HOFFMANN-LA ROCHE INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-6159747-A | Analytical test element with a blister filled with liquid | ROCHE DIAGNOSTICS GMBH (DE) | 2000-12-12 | — | — | US | disclosed |
| US-5731158-A | ENZYME AMPLIFICATION OF DETECTOR SIGNAL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-24 | — | — | US | disclosed |
| US-5583001-A | REACTING WITH A CONJUGATE CONSISTING OF A DETECTABLY LABELED SUBSTRATE SPECIFIC FOR ENZYME SYSTEM; DEPOSITS WHEREVER RECEPTOR IS IMMOBILIZED | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| US-5324650-A | Using a deblocking agent | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0465577-B1 | CATALYZED REPORTER DEPOSITION | DU PONT (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5196306-A | Amplification | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| US-5182203-A | Amplification of detector signals in immunoassays | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-26 | — | — | US | disclosed |
| EP-0465577-A1 | CATALYZED REPORTER DEPOSITION. | DU PONT (US) | 1992-01-15 | — | — | EP | disclosed |
| WO-1990011523-A2 | CATALYZED REPORTER DEPOSITION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-04 | — | — | WO | disclosed |